Concentrations of legacy organochlorine pesticides (OCPs), including dichlorodiphenyltrichloroethane (DDT) and its metabolites (e.g., DDE and DDD), and hexachlorocyclohexanes (HCHs) were determined in 111 soil samples from the Midway Atoll. OCPs were found in all samples analyzed, with predominance of α-HCH, p,p′-DDD and p,p′-DDT. The total concentrations ranged from 0 to 127 ng g?1 with a median concentration of 17 ng g?1 for HCHs and 1.4 to 643 ng g?1 with amedian concentration of 168 ng g?1 for DDTs. The possible degradation pathways and potential sources of DDTs and HCHswere investigated. The total concentrations of DDTs and HCHswere used to evaluate the cancer risk probabilities in humans via ingestion, dermal contact and inhalation of soil particles. Very low cancer risk was found in all soil samples caused by ΣDDTs and ΣHCHs.