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  • Name:  Jungang Chen
  • Title:  Professor
  • Education:  PhD
  • TEL:  027-87702844
  • Email:  chenjungang@wbgcas.cn
  • Address:  Wuhan Botanical Garden, Chinese Academy of SciencesNo. 201 Jiufeng 1 Road, East Lake High-Tech Development Zone, Wuhan, Hubei, P. R. China
  • Research Center: 

    Center for Resource Plants and Speciality Agricultural Plants

    Resume:

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    Major publications:

    1. Wang ZY#, Pan BS#, Manne RK#, Chen JG#, Lv D, Wang M, Tran P, Weldemichael T, Yan W, Zhou H, Martinez GM, Shao J, Hsu C, Hromas R, Zhou D, Qin ZQ*, Lin H*, Li H-Yu*.2025. CD36-mediated endocytosis of proteolysis-targeting chimeras. Cell, 188(12):3219-3237 e3218.
    2. Chen JG, Fan J, Malaviarachchi PA, Post SR, Lin Z, Zhang X, Qin ZQ. 2025. Alterations in Cellular Gene Expression Due to Co-Infection With Kaposi's Sarcoma-Associated Herpesvirus and SARS-CoV-2: Implications for Disease Severity. J Med Virol, 97(1):e70149.
    3. Chen JG, Lin Z, Fan J, Monzavi-Karbassi B, Kelly T, Post SR, Dai L, Qin ZQ. 2024. Identification of new microtubule small-molecule inhibitors and microtubule-associated genes against triple negative breast cancer. Am J Cancer Res, 14(4):1545-1560.
    4. Chen JG, Fan J, Lin Z, Dai L, Qin ZQ. 2024. Human endogenous retrovirus type K encoded Np9 oncoprotein induces DNA damage response. J Med Virol, 96(3):e29534.
    5. Chen JG, Wang Z, Phuc T, Xu Z, Yang D, Chen Z, Lin Z, Kendrick S, Dai L, Li H-yu, Qin ZQ. 2023. Oncolytic strategy using new bifunctional HDACs/BRD4 inhibitors against virus-associated lymphomas. PLOS Pathogens, 19(1):e1011089.
    6. Chen JG, Song J, Plaisance-Bonstaff K, Mu S, Post SR, Dai L, Qin ZQ. 2023. Role of Histamine and Related Signaling in Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis and Oncogenesis. Viruses, 15(4).
    7. Chen JG, Lin Z, Song J, Plaisance-Bonstaff K, James J, Mu S, Post SR, Dai L, Qin ZQ. 2023. Echinomycin as a promising therapeutic agent against KSHV-related malignancies. Journal of Hematology & Oncology, 16(1):48.
    8. Dai L#, Lu YC#, Chen JG#, Plaisance-Bonstaff K, Mu S, Forrest JC, Whitby D, Post SR, Qin ZQ. 2022. Oral Shedding of an Oncogenic Virus Alters the Oral Microbiome in HIV+ Patients. Front Microbiol, 13:882520.
    9. Chen JG, Song J, James J, Plaisance-Bonstaff K, Post SR, Qin ZQ, Dai L. 2022. Activation of IL1 signaling molecules by Kaposi's sarcoma-associated herpesvirus. Front Cell Infect Microbiol, 12:1049624.
    10. Chen JG, Song J, Dai L, Post SR, Qin ZQ. 2022. SARS-CoV-2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era? J Med Virol, 94(11):5103-5111.
    11. Chen JG, Dai L, Kendrick S, Post Steven R, Qin ZQ. 2022. The Anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesvirus Reactivation through Regulation of Intracellular Signaling Pathways. Antimicrobial Agents and Chemotherapy, 66(3):e02395-02321.
    12. Chen JG, Barrett L, Lin Z, Kendrick S, Mu S, Dai L, Qin ZQ.2022. Identification of natural compounds tubercidin and lycorine HCl against small-cell lung cancer and BCAT1 as a therapeutic target. Journal of Cellular and Molecular Medicine, 26(9):2557-2565.
    13. Del Valle L, Dai L, Lin HY, Lin Z, Chen JG, Post SR, Qin ZQ. 2021. Role of EIF4G1 network in non-small cell lung cancers (NSCLC) cell survival and disease progression. J Cell Mol Med, 25(6):2795-2805
    14. Dai L, Jung BG, Chen JG, Samten B, Forrest JC, Post SR, Qin ZQ. 2021. The potential impacts of early secreted antigenic target of 6 kDa of Mycobacterium tuberculosis on KSHV-infected cells. J Med Virol, 93(6):4028-4032.
    15. Chen JG, Dai L, Barrett L, James J, Plaisance-Bonstaff K, Post SR, Qin ZQ. 2021. SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus. Communications Biology, 4(1):682.
    16. Chen JG#, Zhang HW#, Chen XL. 2020. Pemetrexed inhibits Kaposi's sarcoma-associated herpesvirus replication through blocking dTMP synthesis. Antiviral Res, 180:104825.
    17. Chen JG, Lin Z, Barrett L, Dai L, Qin ZQ. 2020. Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG). Bioorg Chem, 99:103847.
    18. Chen JG#, Goyal N#, Dai L#, Lin Z#, Del Valle L, Zabaleta J, Liu J, Post SR, Foroozesh M, Qin ZQ. 2020. Developing new ceramide analogs and identifying novel sphingolipid-controlled genes against a virus-associated lymphoma. Blood, 136(19):2175-2187.
    19. Chen JG, Foroozesh M, Qin ZQ. 2019. Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies. Oncogenesis, 8(1):6.
    20. Chen JG, Del Valle L, Lin HY, Plaisance-Bonstaff K, Forrest JC, Post SR, Qin Z 2019. Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation. Virology, 536:16-19.
    21. Chen JG, Dai L, Goldstein A, Zhang H, Tang W, Forrest JC, Post SR, Chen XL, Qin ZQ. 2019. Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation. PLOS Pathogens, 15(12):e1008156.
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